What is the difference between tenofovir and entecavir

- Dec 12, 2017 -

What is the difference between tenofovir and entecavir?

Tenofovir and entecavir are regarded as first-line anti-hepatitis B virus because of their strong antiviral activity, low resistance and good safety, and Pegasys in interferon. According to the classic clinical trial, one year treatment of tenofovir and entecavir, the anti-virus effects were compared as follows:

HBeAg (+) patients with HBV DNA decreased, tenofovir 1.58 × 10 6th power, entecavir 7.9 × 10 6 copies / ml;

HBeAg (?) Patients with HBV DNA decreased, tenofovir 3.98 × 10 of the fifth power, entecavir 1.00 × 10 copies of 5 copies / ml; lamivudine resistant patients with tenofovir and non-resistance Of patients are equally effective; use of entecavir for adefovir-resistant patients is as effective as non-drug resistant patients.


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